Enrollment Rescue for Glaucoma and Retinal Disease Study

February 9, 2018


A leading pharma company needed assistance to rescue their enrolling ophthalmology study. The sponsor was attempting to complete enrollment for a normative, glaucoma and retinal disease study. With only a few months left for recruitment efforts, enrollment was lagging and would fall short of the target goal. We had less than four months to conceive, develop, and execute a strategy that would succeed in achieving the sponsor’s enrollment goals and timeline.


ThreeWire moved quickly to execute the contract, plan and implement a direct-to-patient media outreach strategy in three distinct markets, which included TV, radio, print, and web-based advertisements. Patients who responded to the media were pre-screened centrally by our Patient Interaction Center® (PIC) and pre-qualified referrals were delivered to sites. We also produced and utilized study-branded patient outreach materials, including brochures, posters, flyers, and launched a study website with an online self-screener that gave potential patients access to important study information and the option to pre-screen 24/7.


We generated our first referral just one day after running media, and contributed our first enrollment just a few weeks after that. Ultimately, our multi-tactic outreach efforts contributed a total of 19 consented patients and 12 enrollments in under two months, enabling the sponsor to close enrollment.

Previous Flipbook
Patient Identification for Phase II OAB Drug Study in Europe
Patient Identification for Phase II OAB Drug Study in Europe

Challenge: Jump start enrollment at a small number of key sites in order to generate momentum for quickly e...

Next Flipbook
Patient Enrollment for Phase IB Tobacco Research Study
Patient Enrollment for Phase IB Tobacco Research Study

Challenge: A top-tier CRO, had been running their study for six months when enrollment, as well as new scre...