Retain 700 subjects who completed the first part of the study into a 52-week extension study across six continents.


ThreeWire developed comprehensive patient retention materials for distribution among global sites. Materials included both site-focused items (e.g., Tips and Techniques for Study Coordinators, Participant Contact Forms and Logs ) and patient-focused items (e.g., study guides, newsletters, greeting cards, certificates of appreciation).


Completed creative development of materials in 13 languages within a month of project award. IRB approved materials were sent electronically to sponsor for printing and distribution.