IRBNet
Experience the industry’s No. 1 IRB management platform that simplifies, streamlines, and saves resources.
There’s a powerful reason WCG’s IRBNet supports some 2,300 IRBs and 250,000 individual users—more than any other automated human research review solution: IRBNet makes managing IRBs more efficient, easier to use and less expensive. This cloud-based platform streamlines IRB management for institutions, providing a scalable, user-friendly solution for protocol review, compliance, and documentation.
Because IRBNet is an extremely robust and scalable tool, it’s likely the only software your institution will ever need. The platform is flexible and affordable enough to handle the needs of small institutions, but it also operates the technology infrastructure of the largest research compliance network in existence.
Since IRBNet is in the cloud, you’ll find it extremely easy to use, quick to implement and inexpensive to maintain—eliminating the need for investments in hardware or IT development and support.

Ethics review processes have become increasingly complex. Managing them doesn’t have to be.
Economical
See the power of significant savings. For institutions that use our IRB for external reviews, the technology solution may be provided at no cost.
Rapid Implementation
Start using IRBNet within 90-120 days versus the standard 6-8 months (or longer).
World-class Customer Service
There’s no waiting with IRBNet; you have direct access to our superb, responsive support team at no additional cost.
Cloud-based
Remote access, automatic system updates, and continual cost savings (no IT resources, ongoing maintenance, or hardware investments required).
Large & Small
Flexible and affordable to handle any site’s needs, leveraging the technology infrastructure of the largest research compliance network in existence.
Compliance & Security
Hosted at a secure, enterprise-class data center that complies with strict requirements of all our members, including the U.S. government.
The Difference Between IRBNet and eReview Manager:
IRBNet is specifically designed as a robust, flexible electronic compliance committee workflow platform, offering comprehensive project management tools, secure cloud-based access, and efficient operations for both large and small institutions. Its core strengths lie in affordability, rapid implementation, and compliance with institutional and government standards — making it particularly suited for universities, healthcare systems, and government research organizations managing institutional IRBs, as well as other research compliance committees.
In contrast, WCG’s ClinSphere eReview ManagerTM is tailored for sponsors, CROs, and research sites seeking to optimize WCG IRB review processes, offering advanced features such as smart workflows, collaboration hubs, automated document management, and real-time status tracking. While IRBNet is optimized for broad institutional oversight and internal IRB management, eReview Manager provides a modern, intuitive user experience for clients needing high-speed study start-up, integration with external systems, and detailed operational support throughout multi-site studies.
Align with the world leader in human research protection.
IRBNet is the only eIRB solution integrated with WCG – an organization with a proven track record of unsurpassed commitment to human research protection and the advancement of the science of human health.
In addition to IRBNet, WCG is a leader in facilitating and expediting clinical trials, most notably through WCG’s IRB Review solution—the most experienced and trusted IRB partner to hospitals, healthcare systems, and Academic Medical Centers (AMCs) in North America.

Getting Started
Getting Started with IRBNet
IRBNet is an enterprise-class, cloud-based platform that requires no software installation, maintenance, or burden on your institution’s IT resources. With a user-friendly Smart Form interface and secure online access, IRBNet supports IRB, IACUC, IBC, and other institutional boards from any location, on any device, delivering flexibility for organizations of all sizes.
Enrollment is simple; pricing is usage-based with no individual user fees, and onboarding — including web-based training — is efficient and tailored to your workflow. Many institutions can be up and running in as little as 48 hours, with unlimited support and training always included. To learn more or see IRBNet in action, contact us today for additional information and to schedule a live demo.
Smarter IRB management awaits.
Knowledge is the key to improvement and advancement. Guide your efforts with the industry’s most-used platform built on decades of ethical review expertise. Lower costs, minimize (if not, eliminate) research errors, increase process transparency, and improve data reporting with the industry’s most complete solution for researchers, coordinators/administrators, members, and boards.
See the power of IRBNet firsthand with an in-depth live demo and consultation.
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