Timely, Targeted Interventions

WCG’s portfolio of interventions reduces risks and improves data quality continuously throughout your clinical trial, ultimately protecting your primary endpoints.

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De-risk trials through timely, targeted interventions

WCG’s portfolio of tailored, evidence-based interventions mitigates the risks of bias, variability and human error in clinical trials, especially those with subjective primary endpoints. The result: improved caliber of data; clearer signals; and standardized, accurate studies.

WCG’s timely, targeted interventions prevent problems and catch them as they arise for continuous study improvement.

Whether it’s through placebo response reduction, accurate symptom reporting, or rater training, our interventions are based on years of clinical expertise and extensive trial experience, firmly grounded in proven concepts of adult learning. Clinical and psychometric experts—including the authors of widely used rating scale instruments—train investigators, research participants and site staff, thereby increasing the validity and clinical meaningfulness of your primary measures.

Your study has no room for imprecision on the part of raters, patients or investigators. Timely, targeted interventions can increase the accuracy and reliability of your clinical trial, giving you a greater chance to attain your primary endpoint.

Schedule a consultation to learn how.


Save your trial. Placebo response frequently leads to study failure. To increase your chances of success, neutralize expectations with Placebo Response Reduction.

Placebo Response Reduction

Improve data accuracy by training patients to assess and report their symptoms more accurately with Accurate Symptom Reporting.

Accurate Symptom Reporting

Ensure consistent scoring with Rater Training qualification and certification.

Rater Training

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Improve Patient-Reported Data with Accurate Symptom Reporting Training

Teaching patients to be more introspective about what’s going on inside their own bodies allows them to report their pain—and other subjective symptoms—more accurately. In effect, you reduce variability and inoculate them against the external cues that drive the placebo response. Patients are trained at the outset and throughout the trial as needed.

WCG has developed and validated the industry-leading training program to improve the accuracy of symptom reporting.

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Neutralize Expectations with Placebo Response Reduction Training

Placebo response leads to failed studies. This is a particular concern in trials with subjective endpoints, where expectation of benefit drives the placebo response. To reduce the placebo response, we must neutralize expectations of treatment benefit.

Our Placebo Response Reduction intervention provides a psychoeducational approach to training for staff and patients alike.

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Ensure Consistent Scoring with Rater Training

Ensure consistent scoring with rater training, qualification and certification. Rater bias, rater errors and rater variability put the quality of clinical data–and the entire trial–at risk.

WCG delivers training based on years of clinical expertise and extensive trial experience that is firmly grounded in proven concepts of adult learning.

Only those raters trained and certified on a particular scale have access to that scale. Moreover, this training is not “once and done.” Rater training begins before the study and continues as needed, providing both prevention and timely intervention.

Because we maintain a constantly updated list of trained raters, we can deploy them quickly when and where they are needed.

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Timely, Targeted Interventions Resources

Want to see how timely, targeted interventions can reduce bias, variability, and human error in your next trial?

We can show you—let’s talk. Complete the form to request and schedule a consultation. We’ll assess your needs, review the right interventions for your study, and demonstrate how you can continuously correct threats to your primary endpoint.